QTL for Body Composition on Chromosome 7 Detected Using a Chromosome Substitution Mouse Strain
نویسندگان
چکیده
منابع مشابه
body composition QTL located on chromosome 7 themuscle tissues in homozygous or heterozygous pigs for Metabolic and histochemical characteristics
30:232-241, 2007. First published 10 April 2007; Physiol. Genomics Florence Gondret Hocquette, Bénédicte Lebret, Nathalie Iannuccelli, Jean-Pierre Bidanel, Denis Milan and Julie Demars, Juliette Riquet, Marie-Pierre Sanchez, Yvon Billon, Jean-François body composition QTL located on chromosome 7 the muscle tissues in homozygous or heterozygous pigs for Metabolic and histochemical characteristic...
متن کاملDevelopment and characterization of a congenic strain carrying Pbwg12, a growth QTL on mouse chromosome 12.
In previous genome-wide QTL studies, Pbwg12 on mouse chromosome 12 was discovered in a gene pool of wild Mus musculus castaneus mice. Pbwg12 does not have a main effect but has an epistatic interaction effect on body weight after birth. In this study, we developed a congenic strain, named B6.Cg-Pbwg12, with an approximately 59-Mb wild-derived genomic region harboring Pbwg12, by recurrent backcr...
متن کاملGenetic analysis of daily physical activity using a mouse chromosome substitution strain.
There is considerable evidence for a genetic basis underlying individual differences in spontaneous physical activity in humans and animals. Previous publications indicate that the physical activity level and pattern vary among inbred strains of mice and identified a genomic region on chromosome 13 as quantitative trait loci (QTL) for physical activity. To confirm and further characterize the r...
متن کاملA novel ATPase on mouse chromosome 7 is a candidate gene for increased body fat.
A region of mouse chromosome 7, just distal to the pink-eyed (p) dilution locus, contains a gene or genes, which we have named p-locus-associated obesity (plo1), affecting body fat. Mice heterozygous for the most distally extending chromosomal deletions of this region have nearly double the body fat of mice when the deletion is inherited maternally as when it is inherited paternally. We have ph...
متن کاملTwo quantitative trait loci for prepulse inhibition of startle identified on mouse chromosome 16 using chromosome substitution strains.
Prepulse inhibition (PPI) of acoustic startle is a genetically complex quantitative phenotype of considerable medical interest due to its impairment in psychiatric disorders such as schizophrenia. To identify quantitative trait loci (QTL) involved in mouse PPI, we studied mouse chromosome substitution strains (CSS) that each carry a homologous chromosome pair from the A/J inbred strain on a hos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Obesity
سال: 2008
ISSN: 1930-7381
DOI: 10.1038/oby.2007.26